Biocompatible macro-initiators controlling radical retention in microfluidic on-chip photo-polymerization of water-in-oil emulsions.
نویسندگان
چکیده
A series of water-soluble macro-initiators is synthesized to avoid radical loss in microfluidic on-chip photo cross-linking of hyaluronic acid methacrylate-containing water-in-oil emulsions. Their superior performance over known photo-initiators through the generation of water-soluble radicals and excellent biocompatibility are demonstrated.
منابع مشابه
Preparation of Reactive and Thermal Stable Hyperbranched Graft Copolymers/ Clay Nanocomposite via ‘Living’ Free Radical Polymerization
Exfoliated poly (Chloromethyl styrene-co-styrene)-g-polyacrylonitryle/organo- modified montmorillonite [P(CMSt-co-St)-g-PAN/O-MMT] nanocomposite was synthesized through solution intercalation method by using atom transfer and nitroxide mediated radical polymerization. At first, poly (chloromethyl styrene-costyrene) copolymer was synthesized by nitroxide - mediated “living” free radical polyme...
متن کاملBiocompatible surfactants for water-in-fluorocarbon emulsions.
Drops of water-in-fluorocarbon emulsions have great potential for compartmentalizing both in vitro and in vivo biological systems; however, surfactants to stabilize such emulsions are scarce. Here we present a novel class of fluorosurfactants that we synthesize by coupling oligomeric perfluorinated polyethers (PFPE) with polyethyleneglycol (PEG). We demonstrate that these block copolymer surfac...
متن کاملControllable microfluidic production of gas-in-oil-in-water emulsions for hollow microspheres with thin polymer shells.
Here we developed a simple and novel one-step approach to produce G/O/W emulsions with high gas volume fractions in a capillary microfluidic device. The thickness of the oil layer can be controlled easily by tuning the flow rates. We successfully used the G/O/W emulsions to prepared hollow microspheres with thin polymer shells.
متن کاملMultiple-channel emulsion chips utilizing pneumatic choppers for biotechnology applications.
The formation of micro-scale monodispersed emulsions is crucial for a variety of applications such as cosmetics, food industry and biotechnology. In this study, a new microfluidic chip with a multiple-channel layout for high-throughput emulsions is reported. This chip generated fine-tuned and uniform microdroplets in liquids with a higher throughput for emulsification applications. It employed ...
متن کاملModification of Polyvinyl Alcohol via Atom Transfer Radical Polymerization for Targeted Drug Delivery Applications
In current study,a hydrogel based on biocompatible polymerwas prepared. The functionalization of polyvinyl alcohol (PVA)with epichlorohydrin(ECH) to produce epichlorohydrin-g-polyvinyl alcohol (PVA/ECH) as a suitable macroinitiator for atom transfer radical polymerization (ATRP) reaction was investigated.ThenN-vinyl pyrrolidone (NVP) waspolymerized on the surface of macroinitiatorin presence of...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Chemical communications
دوره 50 1 شماره
صفحات -
تاریخ انتشار 2014